Mander worked with the noted environmentalist, David Brower, managing the Sierra Club’s advertising campaigns to prevent the construction of dams in the Grand Canyon, to establish Redwood National Park, and to stop the U.S. Supersonic Transport (SST) project. In 1971 he founded the first non-profit advertising agency in the United States, Public Interest Communications.
Mander was the executive director of the International Forum on Globalization, which he founded in 1994, until 2009, and continued to serve on its staff as a Distinguished Fellow. He was also the program director for Megatechnology and Globalization at the Foundation for Deep Ecology. Mander is sometimes said to be part of the Neo-Luddite movement.
In 2007 Jerry Mander appeared in the full-length documentary film, What a Way to Go: Life at the End of Empire.
Jerry Mander was a resident of Bolinas, California, since 1977 until his passing in April 2023.